Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8552078 | Reproductive Toxicology | 2018 | 24 Pages |
Abstract
Genistein is a phytoestrogen found in soy. We previously found that adult exposure to dietary levels of genistein affected gestation time, parturition time, litter size, pup weight, and pup mortality in CD-1 mice. The present study investigated the effects of adult genistein exposure on follicle number and gene expression in the ovaries of CD-1 mice. We found that exposure to genistein had no effect on follicle number, but it did affect the expression of apoptotic regulatory genes (Bax, Bcl-2, Bid, and Dffa) in the ovary.
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Authors
Payel Kundu, Shreya Patel, Daryl D. Meling, Kassie Deal, Liying Gao, William G. Helferich, Jodi A. Flaws,