Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8553163 | Toxicology Letters | 2018 | 18 Pages |
Abstract
The highest resistance was observed for cisplatin. The SM resistant cells revealed changes in the miRNA profile as described before. The resistance to cisplatin is also connected to a specific miRNA profile. Interestingly, changes of miRNA-203 and miRNA-21 levels were found in HaCaT/SM as well as in cisplatin resistant cells. It is therefore conceivable that the same resistance pathways are involved for both substances.
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Authors
Annette Schmidt, Markus Wolf, Simone Rothmiller, Franz Worek, Dirk Steinritz, Horst Thiermann,