| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8553201 | Toxicology Letters | 2018 | 20 Pages |
Abstract
This study has demonstrated that CPAP, initiated before overt signs of exposure become manifest, significantly improved survival as well as improving some clinically relevant physiological measures of phosgene-induced acute lung injury over 24Â h.
Keywords
Commercial Off the ShelfARDSPEEPSao2PaO2O2HbTICCPAPPaCO2BALWBCIPPVOxyhaemoglobinCOTSAcute lung injuryInhalationelectrocardiogramECGAlistandard deviationSurvivalCOPDChronic obstructive pulmonary diseaseanalysis of varianceANOVAintermittent positive pressure ventilationIntravenousTreatmentAcute respiratory distress syndromephosgenePositive end expiratory pressureContinuous positive airway pressurebronchoalveolar lavageEndotracheal tubeToxic industrial chemicalwhite blood cellPorcine
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Authors
Stuart Graham, Sarah Fairhall, Steve Rutter, Philippa Auton, Rachel Rendell, Adam Smith, Rosi Perrott, Tim Nicholson Roberts, Bronwen Jugg,