Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8553306 | Toxicology Letters | 2018 | 33 Pages |
Abstract
Our findings indicate that oral exposure to a low dose AgNPs induces detrimental effect on memory and cognitive coordination processes. The presence of silver ions rather than AgNPs in different brain regions, in particular the hippocampus, suggests crucial role of silver ions in AgNPs-induced impairment of the higher brain functions.
Keywords
TPLNOAELCMTi.v.tmaxMWMNanoSIMSGPXb.w.ALTAgNPsROSASTAspartate aminotransferaseAlanine aminotransferaseALPAlkaline phosphataseTarShort term memoryIntravenousBBBSpeedWalking speedLinMorris water mazeblood-brain-barrierBrainSilver nanoparticlesSilverno observable adverse effect levelbody weightglutathione peroxidaseReactive oxygen species
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
M. WÄsierska, K. Dziendzikowska, J. Gromadzka-Ostrowska, J. Dudek, H. Polkowska-Motrenko, J.N. Audinot, A.C. Gutleb, A. Lankoff, M. Kruszewski,