| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8553505 | Toxicology Letters | 2018 | 33 Pages |
Abstract
- Caffeine induced a hypersensitivity of HPA axis in adult offspring rats.
- Caffeine increased the potential excitability of hypothalamus in offspring rats.
- Caffeine induced a high expression of hippocampal GAD67 in offspring rats.
Keywords
Tbr2α-CaMKIIIUGRACTHMASH1post-synaptic density 95prenatal caffeine exposureADORA2Aglutamic acid decarboxylase 65PSD95GAD65VGLUT2Pax6AVPSPFCRHglutamic acid decarboxylase 67PCEGad67cAMPβ-actinCyclic adenosine monophosphatePaired box 6Hypersensitivityvesicular glutamate transporter 2specific pathogen-freedentate gyrusintrauterine growth retardationHypothalamic-pituitary-adrenal axisHPAadrenocorticotropic hormonecorticotrophin-releasing hormonehypothalamic-pituitary-adrenalHippocampusarginine vasopressinCaffeineCORTCorticosteroneGlucocorticoidAdenosine A2A receptor
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Authors
Dan Xu, Chong Zhang, Xia He, Zijing Guo, Dongcai Hu, Juan Lu, Siyuan Cheng, Hui Wang,