Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8553545 | Toxicology Letters | 2018 | 12 Pages |
Abstract
Human health-based limit values based on an external dose metric without sufficient knowledge on kinetics might be too high to be sufficiently protective. Insight in the actual internal exposure, the toxic agent, the appropriate dose metric, and whether an effect is related to internal concentration or dose is important. Without this, application of assessment factors on an external dose metric and the conversion to continuous exposure results in an uncertain human health risk assessment of inhalation exposures.
Keywords
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Health, Toxicology and Mutagenesis
Authors
Liesbeth Geraets, Marco J. Zeilmaker, Peter M.J. Bos,