Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8553872 | Toxicology in Vitro | 2018 | 31 Pages |
Abstract
A proposed model of molecular iteraction to delineate the actin mechanisms of 1,4-benzoquinone in HL60 cell. 1,4-benzoquinone, a metabolite of benzene, decreases mitochondrial membrane potential (MMP), increases in reactive oxygen species (ROS), and activates the PINK1/Parkin pathway mitophagy that plays a protective role in apoptosis.
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Authors
Chunxiao Zhang, Xiuyuan Yu, Jiahao Gao, Qianqian Zhang, Shuqiang Sun, Hua Zhu, Xinjun Yang, Hongtao Yan,