Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8553981 | Toxicology in Vitro | 2018 | 30 Pages |
Abstract
We conclude that a modified RhE skin irritation test has the potential to address the skin irritation potential of the medical devices. Standardization and focus on the technical issues is essential for accurate prediction.
Keywords
ET50SDSTechnical CommitteeEpiDermRHESOPDPBSOECDMTTLactic acidHeptanoic acidReconstructed human epidermisReconstructed epidermisISOMedical devicesSkin irritationManagement teamIn vitrotest guidelinestandard operating procedureSesame oilthe Organisation for Economic Co-operation and Developmentsodium dodecyl sulphateDulbecco's phosphate buffered salineVehicle controlnegative controlpositive controls
Related Topics
Life Sciences
Environmental Science
Health, Toxicology and Mutagenesis
Authors
Kandarova Helena, Willoughby Jamin A., De Jong Wim H., Letasiova Silvia, Milasova Tatiana, Bachelor Michael A., Breyfogle Bridget, Yuki Handa, De la Fonteyne Liset, Coleman Kelly P.,