A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases

Article ID	Journal	Published Year	Pages	File Type
8553990	Toxicology in Vitro	2018	36 Pages	PDF

Keywords

5caC 5FU DNMTs tert-butylhydroperoxide 5hmC DNA methyltransferases BER TET DEGs 8-oxodG SAM CPDB tBH 5hmU 5fC 5mC 5-formyluracil 5-formylcytosine 5-Methylcytosine 5-hydroxymethylcytosine 5-carboxylcytosine 8-oxo-7,8-dihydro-2′-deoxyguanosine HCC ROS S-adenosylmethionine base excision repair ten-eleven translocation HepG2 cells tert-butyl hydroperoxide Differentially expressed genes Hepatocellular carcinoma Reactive oxygen species

Related Topics

Life Sciences Environmental Science Health, Toxicology and Mutagenesis

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A cross-omics approach to investigate temporal gene expression regulation by 5-hydroxymethylcytosine via TBH-derived oxidative stress showed involvement of different regulatory kinases

Authors

Jacob J. Briedé, Lize Deferme, Jarno E.J. Wolters, Sandra M.H. Claessen, Twan van den Beucken, Richard J. Wagner, Simone G. van Breda, Jos C.S. Kleinjans,