Article ID Journal Published Year Pages File Type
855891 Procedia Engineering 2015 4 Pages PDF
Abstract

We present a method to supply oxygen to on-chip stored aqueous droplets surrounded by oxygen-permeable fluorinated oil in micro-channels. By generating air-droplets (air-bubbles) in between the aqueous droplets, oxygen diffuses to those aqueous droplets. This is confirmed by experiments comparing the effect of nitrogen bubbles and air-bubbles. The proposed method and device are a step towards long-term on-chip cultivation of mammalian cells and aerobic bacteria growth in droplets.

Related Topics
Physical Sciences and Engineering Engineering Engineering (General)