| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8586792 | Clinical Nutrition | 2018 | 11 Pages |
Abstract
The study shows for the first time that supplemented microalgae DHA ameliorates disease activity in patients with RA along with a shift in the balance of AA- and DHA-derived lipid mediators towards an anti-inflammatory/pro-resolving state.
Keywords
MUFAn-3 long-chain polyunsaturated fatty acidsn-3 LC-PUFADGLADAS28DMARDsHAQRRSFFP5-LOXGLASFARBCALANSAIDSCOXLPSDPAESREPARed blood cells5-LipoxygenaseTbxγ-linolenic acidRheumatoid arthritiscyclooxygenasedihomo-γ-linolenic acidα-linolenic acidArachidonic acidEicosapentaenoic aciddocosapentaenoic aciddocosahexaenoic acidLinoleic acidhydroxy-eicosatetraenoic acidFatty acidsaturated fatty acidsmonounsaturated fatty acidsinflammationThromboxanesNutritionNonsteroidal anti-inflammatory drugsdisease-modifying antirheumatic drugsDocosanoidsDHALeukotrieneslipopolysaccharidefatty acid methyl estersFAME یا fatty acid methyl esters Disease activity scoreHETEHealth questionnaireC-reactive proteinCRPProstaglandinsPlasma lipids
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Authors
C. Dawczynski, M. Dittrich, T. Neumann, K. Goetze, A. Welzel, P. Oelzner, S. Völker, A.M. Schaible, F. Troisi, L. Thomas, S. Pace, A. Koeberle, O. Werz, P. Schlattmann, S. Lorkowski, G. Jahreis,