Theobromine does not affect postprandial lipid metabolism and duodenal gene expression, but has unfavorable effects on postprandial glucose and insulin responses in humans

Article ID	Journal	Published Year	Pages	File Type
8586931	Clinical Nutrition	2018	9 Pages	PDF

Abstract

This trial was registered on clinicaltrials.gov under study number NCT02209025.

Keywords

IPA DAUC Apolipoprotein B48 apoB48 Theobromine CYP1A2 ApoB100 IAUC CYP2E1 hsCRP GSEA HDL-C ApoA-I FFQ LDL-C SBP DBP FFA Apolipoprotein A-I apolipoprotein B100 Free fatty acid Cardiovascular diseases Ingenuity Pathway Analysis Gene Set Enrichment Analysis triacylglycerol TAG یا triacylglycerols CVD Microarray cytochrome P450 1A2 cytochrome P450 2E1 diastolic blood pressure systolic blood pressure high-density lipoprotein cholesterol Lipid metabolism Glucose metabolism incremental area under the curve food frequency questionnaires high sensitivity C-reactive protein Postprandial low density lipoprotein cholesterol

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Theobromine does not affect postprandial lipid metabolism and duodenal gene expression, but has unfavorable effects on postprandial glucose and insulin responses in humans

Authors

Lotte Smolders, Ronald P. Mensink, Mark V. Boekschoten, Rogier J.J. de Ridder, Jogchum Plat,