Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8587021 | Clinical Nutrition | 2018 | 5 Pages |
Abstract
Our study provided evidence that the MTR c.2756A>G polymorphism is associated with MTHFR amplicon hypomethylation in VPA-treated patients with epilepsy.
Keywords
Long interspersed nucleotide element-1AEDMTRMTHFROCMNTDSMTRRHWEBHMTHcyEpilepsyANOVAone-way analysis of varianceHardy–Weinberg equilibriumLINE-1antiepileptic drugValproateFolateOne-carbon metabolismDNA methylationMethylenetetrahydrofolate reductaseMethionine synthasemethionine synthase reductaseNeural tube defectshomocysteineSingle nucleotide polymorphismsSingle nucleotide polymorphismSNP
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Authors
Guanzhong Ni, Jiaming Qin, Ziyi Chen, Hongliang Li, Jueqian Zhou, Min Huang, Liemin Zhou,