Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8591123 | The Ocular Surface | 2018 | 32 Pages |
Abstract
This clinical trial design using a controlled environment and the identified tear biomarkers could be useful to objectively select target patients, to define stress response, and to evaluate therapeutic endpoints in clinical trials.
Keywords
NCEDEDRegulated upon Activation, Normal T cell Expressed and SecretedHLA-DRMCP-1MDSACETNFFMLEGFMMPMIPReceptor antagonistHuman leukocyte antigeninterferonIFNinterleukinDry eye diseasefold changeModerateCytokineSevereEnvironmental conditionsepidermal growth factorconfidence intervaltumor necrosis factorMetalloproteinaseRANTESMultidimensional scalingNADAmacrophage inflammatory proteininterferon gamma-induced proteinpolyvinyl alcohol
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Authors
José Pinto-Fraga, Amalia EnrÃquez-de-Salamanca, Margarita Calonge, MarÃa J. González-GarcÃa, Alberto López-Miguel, Alberto López-de la Rosa, Carmen GarcÃa-Vázquez, Virginia Calder, Michael E. Stern, Itziar Fernández,