Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8595050 | Journal of Stroke and Cerebrovascular Diseases | 2018 | 15 Pages |
Abstract
An S1P1-selective agonist enhanced leptomeningeal collateral circulation via eNOS phosphorylation and promoted postischemic angiogenesis with reinforced blood-brain barrier integrity in a mouse model of acute ischemic stroke, leading to smaller infarct volume and better neurological outcome.
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Authors
Eri MD, Satoru MD, PhD, Motohiro MD, FuYing MD, Masahiko MD, PhD, Kazunori MD, PhD, Takanori MD, PhD,