Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8595517 | Journal of Stroke and Cerebrovascular Diseases | 2018 | 4 Pages |
Abstract
We report a case of a 48-year-old woman with multiple cerebral infarctions caused by nonbacterial thrombotic endocarditis (NBTE) because of adenomyosis with high serum carbohydrate antigen (CA)125 level. Transesophageal echocardiography (TEE) showed a vegetation, 4âmm in diameter, adjacent to the anterior leaflet of the mitral valve on day 2. Soluble CA125 level was elevated to 901âU/mL. Intravenous infusion of unfractionated heparin sodium was started. On day 35, TEE revealed reduction of the vegetation in size, 2âmm in diameter. On day 38, she was transferred to the hospital for further rehabilitation. CA125 is a transmembrane mucin that contributes to the progression of epithelial ovarian cancer. It is important to keep in mind that adenomyosis with abnormally high serum CA125 level may be at high risk of NBTE.
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Authors
Kenji MD, Takahiro PhD, Heisuke PhD, Kenji PhD, Hana PhD, Kensuke PhD, Yasuhiro PhD,