Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8595972 | Journal of Stroke and Cerebrovascular Diseases | 2017 | 14 Pages |
Abstract
The next generation of stroke therapy can apply a polypharmacology strategy for which drugs are designed to target multiple ion transporters/channels or their interaction with neurotoxic signaling pathways. But a successful translation of neuroprotectants relies on in-depth analyses of cell death mechanisms and suitable animal models resembling human stroke.
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Authors
Hui-Jie BS, Mingke PhD,