Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8605099 | The Journal of Pain | 2018 | 14 Pages |
Abstract
This study provides evidence that inflammation of the rat vestibule induces a phenotype recapitulating behavioral and cytological features of human vestibulodynia. The model confirms a crucial role of the local inflammatory renin-angiotensin system in hypersensitivity and hyperinnervation. Targeting this system holds promise for developing new nonopioid analgesic treatment strategies.
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Authors
Anuradha Chakrabarty, Zhaohui Liao, Ying Mu, Peter G. Smith,