Pneumatosis From Esophagus to Rectum: A Comprehensive Review Focusing on Clinico-Radiological Differentiation Between Benign and Life-Threatening Causes

Pneumatosis of the alimentary tract may occur from the esophagus to rectum as a result of a wide spectrum of conditions that range from benign to life-threatening. Although distinguishing between these 2 groups is of paramount importance for an appropriate clinical management, it still remains a challenge for the radiologist in the daily practice. In the light of the current literature, we provide in the present article a comprehensive review focusing on the clinical, laboratory, and radiological findings that most consistently may allow such a differentiation. We also provide a pictorial essay illustrating this range of diagnoses, briefly discussing each one.