Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8615660 | Clinical Lymphoma Myeloma and Leukemia | 2018 | 22 Pages |
Abstract
The major mechanism by which NHL patients develop hypercalcemia is not mediated by calcitriol or PTHrP. Hypercalcemia is most prevalent in patients with diffuse large B-cell lymphoma of the nongerminal cell subtype. Patients with calcitriol-mediated hypercalcemia showed a trend toward worse outcomes, suggesting that calcitriol might be a marker of high-grade lymphoma, transformation to such, or a surrogate for more advanced disease.
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Authors
Rory M. Shallis, Rachel S. Rome, John L. Reagan,