Article ID Journal Published Year Pages File Type
8624289 Journal of the American Society of Cytopathology 2018 20 Pages PDF
Abstract
FISH is reliable for determining HER2 status in cytopathology specimens. Discordant results between cytologic and surgical specimens are uncommon; possible explanations include genetic heterogeneity or inherent molecular changes associated with disease progression and therapies that occur between testing of the primary carcinoma and the metastasis.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Clinical Biochemistry
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HER2 FISH concordance in breast cancer patients with both cytology and surgical pathology specimens
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