| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8624325 | Journal of Oral Biosciences | 2017 | 4 Pages |
Abstract
This review describes the biological characterization of gingipains, which inactivate PI3K and Akt, and disorder the PI3K/Akt signaling pathway. Hence, gingipains may decrease cellular physiological functions, eventually disrupting the gingival epithelium and causing development of periodontal diseases.
Keywords
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Authors
Masaaki Nakayama, Naoya Ohara,