Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8624545 | Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) | 2018 | 44 Pages |
Abstract
The impact of freshwater fish consumption on the status of long-chain n-3 fatty acids (n-3 LCPUFA) in infants in landlocked, low-income populations is unknown. We used secondary data from a randomized, single-blinded, controlled trial to evaluate the impact of daily consumption of complementary food products with small amounts of freshwater fish on whole blood n-3 LCPUFA in Cambodian infants. Infants (nâ¯=â¯419), received daily, one of four food products for 9 months. Two products contained freshwater fish: WinFood (10% fish by dry weight) and WinFood-L (12% fish by dry weight), while two products were non-fish-based: corn-soy blends (CSB+ and CSB++). Whole blood fatty acids and breastfeeding status were assessed at baseline and endline of the intervention. The WinFood products contributed to an estimated maximum intake of 86.5â¯mg/day n-3 LCPUFA. There was no difference in whole blood n-3 LCPUFA among the four intervention groups or between the fish-based and the non-fish-based groups (pâ¯â¥â¯0.142). At endline, 71% of the children were still breastfed. Interaction analyses indicated a lower ratio of n-6/n-3 PUFA in non-breastfed infants in the WinFood groups compared to the CSB groups (pinteraction=â¯0.026). Thus, a high intake of n-3 LCPUFA from breastmilk may have blurred a potential impact of small amounts of freshwater fish effect on n-3 LCPUFA status in Cambodian infants.
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Authors
Mulia Nurhasan, Nanna Roos, Jutta KH Skau, Frank T Wieringa, Henrik Friis, Kim F Michaelsen, Marjoleine A Dijkhuizen, Ken D Stark, Christian Ritz, Chamnan Chhoun, Lotte Lauritzen,