| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8624609 | Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) | 2018 | 14 Pages |
Abstract
Dietary fat quality, especially the intake of specific types of fatty acids, impacts the risk of many chronic diseases, including cardiovascular diseases, certain cancers and type 2 diabetes (T2DM). A recent pooled analysis involving 20 studies from around the world revealed that higher linoleic acid (18:2n-6 LA) biomarker is associated with dose-dependent decreases in the incidence of T2DM. This latest study corroborates earlier cross-sectional studies and intervention trials showing that biomarkers of LA intake are associated with reduced risk of T2DM and better glycemic control and/or insulin sensitivity. This review highlights key clinical trials that have evaluated the role of LA in glycemia and the related condition, insulin sensitivity.
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Authors
Martha A. Belury, Rachel M. Cole, Deena B. Snoke, Taylor Banh, Austin Angelotti,