Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8624650 | Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA) | 2017 | 32 Pages |
Abstract
In a severe trauma model, sustained changes in terms of lung injury and inflammation are determined at day 3 post-trauma. Specifically, increased LTB4 in this porcine long-term model indicated a rapid inflammatory alteration both locally and systemically. The results support the concept of LTB4 as a biomarker for PC after severe trauma and lung contusion.
Keywords
CXCRCVPCAEBALFiO2ATLSARDSDNAdeoxyribonucleic acidCOPDChronic obstructive pulmonary diseaseELISAEnzyme-linked immunosorbent assayAcute respiratory distress syndromeCentral venous pressureBronchoalveolar lavage fluidbody weightAdvanced Trauma Life SupportFraction of inspired oxygenchloroacetate esteraseCXC chemokine receptor
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Authors
Philipp Störmann, Birgit Auner, Lukas Schimunek, Rafael Serve, Klemens Horst, Tim-P. Simon, Roman Pfeifer, Kernt Köhler, Frank Hildebrand, Sebastian Wutzler, Hans-Christoph Pape, Ingo Marzi, Borna Relja,