| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8624901 | Bone | 2018 | 10 Pages |
Abstract
Our data provide evidence that N-BP activate the MEK5/ERK5 cascade and reveal an essential role of ERK5 in osteogenic differentiation and mineralization of skeletal precursors.
Keywords
eNOSPTHLHALPLN-BPKLFFDPsOPNIPPHUVECANTMSCshRNAERK53-hydroxy-3-methylglutaryl coenzyme A reductaseMAPKsmall hairpin RNAAlkaline phosphataseOsteoblastOsteopontinStatinBone mineralizationisopentenyl pyrophosphateBisphosphonateanalysis of varianceANOVAscrambledOsteogenic differentiationHuman umbilical vein endothelial cellEndothelial cellMesenchymal stem cellendothelial nitric oxide synthaseKrüppel-like factorfarnesyl pyrophosphate synthasenitrogen-containing bisphosphonatemitogen-activated protein kinaseOsteoporosisSCR
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Authors
Christian Adam, Lucia Glück, Regina Ebert, Matthias Goebeler, Franz Jakob, Marc Schmidt,