| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8625657 | Current Opinion in Genetics & Development | 2018 | 7 Pages |
Abstract
Cellular fate reprogramming holds great promise to generate functional cell types for replenishing new cells and restoring functional loss. Inspired by transcription factor-induced reprogramming, the field of cellular reprogramming has greatly advanced and developed into divergent streams of reprogramming approaches. Remarkably, increasing studies have shown the power and advantages of small molecule-based approaches for cellular fate reprogramming, which could overcome the limitations of conventional transgenic-based reprogramming. In this concise review, we discuss these findings and highlight the future potentiality with particular focus on this new trend of chemical reprogramming.
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Authors
Xiang Li, Jun Xu, Hongkui Deng,