Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8626166 | International Journal of Developmental Neuroscience | 2018 | 19 Pages |
Abstract
Our data demonstrated that serum estradiol levels directly associated with adipose tissue cholesterol efflux; however, the relationships may be sex-dependent. We discussed our results in the context of currently available data regarding sex-dependent variability in adipose tissue function and HDL-C metabolism as a potential contributor to higher rates of vascular dementia in men. Further research is required to understand the sex-dependent and âindependent variabilities in adipose tissue metabolism to determine novel targets for interventions to prevent the development of vascular dementia.
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Authors
Fatima Iqbal, William J. Durham, Ayyash Melhem, Saleem Raslan, Tony T. Tran, Traver J. Wright, Rabia Asghar, Ken Fujise, Elena Volpi, Labros Sidossis, Nicola Abate, Melinda Sheffield-Moore, Demidmaa Tuvdendorj,