Article ID Journal Published Year Pages File Type
8626334 Placenta 2018 11 Pages PDF
Abstract
A single course of BET alters placental glucocorticoid metabolism in a sex-specific manner. Decreased 11β-HSD2 levels in term born females may lead to an increased placental transfer of maternal cortisol and therefore result in a reduced head circumference and a higher risk for altered stress response in adulthood. Further research is needed to conclude the significance of increased 11β-HSD2 levels in males.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
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