| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8627474 | Best Practice & Research Clinical Endocrinology & Metabolism | 2017 | 45 Pages |
Abstract
Milk is a unique and complete nutritive source for the mammal neonate, also providing immune protection and developmental signals. Lactation is a complex process, proper to the mother and child dyad, and including numerous variables ranging from psychological aspects to the secretory functioning of the mammary epithelial cells, all contributing to a successful breastfeeding. This review gives an integrated overview of the physiology of lactation with a particular focus on cellular and molecular mechanisms involved in milk product secretion and their regulations.
Keywords
feedback inhibitor of lactationMFGSNAREECMPRLAQP5-hydroxytryptamineTGFFGFVAMPMVBHPLXORTEB5-HTGnRHMMPEGFAPMACTHBasolateral plasma membraneIGFMECLTFXanthine oxidasePLIN2aquaporinTight junctionPolyunsaturated fatty acidPUFAoxytocinimmunoglobulin interleukinmultivesicular bodyFilbutyrophilinbpmtransforming growth factorSecretionExtracellular vesiclesMammary epithelial cellendoplasmic reticulumMilkLactationBreastfeedingSNAPepidermal growth factorMammary glandbasement membraneApical plasma membranefibroblast growth factorInsulin-like growth factorlipid dropletHuman placental lactogenLactoferrinExtracellular matrixMatrix metalloproteaseMicro-RNAMiRNAadrenocorticotropic hormoneGonadotropin-releasing hormonefollicle stimulating hormoneluteinizing hormoneGrowth hormoneFSHSecretory vesicleTerminal end budVesicle-associated membrane proteinsynaptosomal-associated proteinprostaglandinProlactinMilk fat globuleGlucocorticoidsoluble N-ethylmaleimide-sensitive factor attachment protein receptor
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Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Sandrine (Scientist, Cell Biologist), Edith (Technician, Physiologist),