Article ID Journal Published Year Pages File Type
8628786 Cytokine 2018 13 Pages PDF
Abstract
In conclusion, TGFβ1 may be an intermediary between SP/NK1R activation and SIGIRR expression in Sp1 siRNA-transfected macrophages. In addition, Sp1 modulates TGFβ1/Smad signaling and negatively regulates SIGIRR protein production by macrophages after SP stimulation.
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Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Preview
Transcription factor specificity protein 1 modulates TGFβ1/Smad signaling to negatively regulate SIGIRR expression by human M1 macrophages stimulated with substance P
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