Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8628964 | Cytokine | 2018 | 5 Pages |
Abstract
Our present observations show that the circulating levels of VEGF and other suggested therapeutic growth factors are significantly increased along with increasing ischemia. These findings present a new perspective to anticipated positive effects of gene therapies utilizing VEGF, HGF, and bFGF, because the levels of these growth factors are endogenously high in end-stage PAD.
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Authors
Juho Jalkanen, Olli Hautero, Mikael Maksimow, Sirpa Jalkanen, Harri Hakovirta,