| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8628984 | Cytokine | 2018 | 4 Pages |
Abstract
The “danger” model of immunology states that the immune system detects and responds to danger by releasing endogenous molecules called alarmins. Strenuous exercise perturbs physiological homeostasis, increasing circulating alarmins to drive the inflammatory response. We describe a working concept of exercise-induced High Mobility Group Box (HMGB)1, a prototypical alarmin, in modulating immune responses and adaptations.
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Authors
Jorming Goh, Michael Behringer,