Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8629194 | Cytokine | 2018 | 6 Pages |
Abstract
Our results demonstrate that AF development and progression (from paroxysmal to persistent) is associated with a gradual increase in serum levels of NT-proBNP, IL-6 and MMP-9/TIMP-1 ratio. Moreover, this study suggests that the relationship between TGF-β1, NT-proBNP and LA diameter allows for the progression of atrial remodeling during AF, despite compensatory changes in the TGF-β1 signaling pathway.
Keywords
ECMIL-6TGF-β1MMP-9IQRN-terminal prohormone of brain natriuretic peptideTIMP-1NT-proBNPstandard deviationinterleukin-6tissue inhibitor of metalloproteinase-1Atrial remodelingTransforming growth factor-beta 1Atrial fibrillationleft atrial diameterExtracellular matrixMatrix metalloproteinase-9interquartile range
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Authors
Adina Elena Stanciu, Radu Gabriel Vatasescu, Marcel Marian Stanciu, Nafija Serdarevic, Maria Dorobantu,