| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8629304 | Cytokine | 2018 | 4 Pages |
Abstract
The reduced release of TNFα and IP-10 after ex vivo blood stimulation with endotoxin is independently associated with poor outcome after stroke. Our results suggest that the inhibition of both the MyD88-dependent pathway and MyD88-independent pathway of TLR4 signaling in blood cells correlates with an unfavorable prognosis in stroke patients.
Keywords
infgranulocytemacrophage colony-stimulating factorIQSTNFIP-10RAGETLR4NIHSSGM-CSFHMGB1MYD88LPSDAMPsMRSTRIFinflammationdamage-associated molecular patternsinterferoninterleukinStrokeCytokinestumour necrosis factorlipopolysaccharideModified Rankin scaleNational Institute of Health Stroke ScaleOutcomeHigh mobility group box 1Toll-like receptor 4
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Elzbieta Klimiec, Katarzyna Kowalska, Paulina Pasinska, Joanna Pera, Agnieszka Slowik, Tomasz Dziedzic,