| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8629394 | Cytokine | 2018 | 5 Pages |
Abstract
High levels of IL-6 and IL-8 characterize early-on IPF-AEs and an increase in the levels of IL-6 and IL-8 associates with worse outcome in all patients. However, as the most representative pro-fibrotic cytokines, TGF-β, IL-10, IL-4 and IL-13 were not increased and given the dualistic nature, both pro-inflammatory and pro-fibrotic of IL-6 further studies are necessary to clarify the enigma of IPF-AEs etiopathogenesis.
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Authors
Spyros A. Papiris, Ioannis P. Tomos, Anna Karakatsani, Aris Spathis, Ioanna Korbila, Antonis Analitis, Likurgos Kolilekas, Konstantinos Kagouridis, Stylianos Loukides, Petros Karakitsos, Effrosyni D. Manali,