| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8629556 | Cytokine | 2017 | 6 Pages |
Abstract
In conclusion, production of IL-23 is differentially regulated in M1 macrophages by SIGIRR through TLR4- or TLR7/8-mediated signaling. SIGIRR is both a negative regulator of TLR4 and a positive regulator of TLR7/8.
Keywords
TRAF6granulocytemacrophage colony-stimulating factorSIGIRRIL-12p40IL-23KLF2IRFHNETLRLPSMAPKSmall interfering RNAsiRNASp1Human neutrophil elastaseinterleukinEnzyme-linked immunosorbent assayELISAParTIRToll-like receptorinterferon regulatory factorinterferon regulatory factor 5Kruppel-like factor 2granulocyte–macrophage colony-stimulating factortumor necrosis factor receptor-associated factor 6lipopolysaccharideSpecificity protein 1mitogen-activated protein kinaseToll/interleukin-1 receptorprotease-activated receptor
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Authors
Rui Yamaguchi, Arisa Sakamoto, Takatoshi Yamamoto, Shinji Narahara, Hiroyuki Sugiuchi, Yasuo Yamaguchi,