Abnormalities in the relationship of paraoxonase 1 with HDL and apolipoprotein A1 and their possible connection to HDL dysfunctionality in type 2 diabetes

Article ID	Journal	Published Year	Pages	File Type
8629963	Diabetes Research and Clinical Practice	2018	9 Pages	PDF

Abstract

Impaired anti-oxidant and anti-atherogenic HDL properties associated with weakened PON1 function and lipid peroxidation may contribute to the development of atherosclerosis-related diseases in T2DM.

Keywords

HDL-C PGC Non-high density lipoprotein cholesterol GGC apoB T2DM HbA1c PON1 OAD ApoA-I RGC LPO LDL-C MPO Apolipoprotein A-I Apolipoprotein B cardiovascular disease Triglycerides Type 2 diabetes CVD body mass index BMI non-HDL-C Non-HDL-Cholesterol high-density lipoprotein cholesterol myeloperoxidase glycated haemoglobin Paraoxonase 1 Lipid peroxides total cholesterol Low-density lipoprotein cholesterol

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology

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Abnormalities in the relationship of paraoxonase 1 with HDL and apolipoprotein A1 and their possible connection to HDL dysfunctionality in type 2 diabetes

Authors

Alena Viktorinova, Ingrid Jurkovicova, Lubomira Fabryova, Sona Kinova, Michal Koren, Anna Stecova, Klara Svitekova,