| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8631653 | Growth Hormone & IGF Research | 2018 | 9 Pages |
Abstract
Our results show that GH action is positively associated with an increase in WAT collagen content as well as a decrease in adipocyte size, particularly in the subcutaneous depot. This effect appears to be due to GH and not IGF-1 and reveals a novel means by which GH regulates WAT accumulation.
Keywords
GHAMmpsGrowth hormone receptor knockoutTissue inhibitors of MMPsBGHGHRTIMPsIGF-1RetroperitonealECMMesentericGrowth hormone receptor antagonistAdipose tissueWhite adipose tissuesubcutaneousinsulin-like growth factor 1FibrosisExtracellular matrixMatrix metalloproteinasesMeSGrowth hormonebovine growth hormoneperiWATgrowth hormone receptorretro
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Authors
Lara A. Householder, Ross Comisford, Silvana Duran-Ortiz, Kevin Lee, Katie Troike, Cody Wilson, Adam Jara, Mitchell Harberson, Edward O. List, John J. Kopchick, Darlene E. Berryman,