| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8632321 | Journal of Diabetes and its Complications | 2018 | 38 Pages |
Abstract
AGE-albumin diminishes ABCA1 by accelerating its degradation through the proteasomal and lysosomal systems. This may increase lipid accumulation in macrophages by diminishing cholesterol efflux via RAGE signaling contributing to atherosclerosis in diabetes mellitus.
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Authors
Rodrigo Tallada Iborra, Adriana Machado-Lima, Ligia Shimabukuro Okuda, Paula Ramos Pinto, Edna Regina Nakandakare, Ubiratan Fabres Machado, Maria Lucia Correa-Giannella, Russell Pickford, Tom Woods, Margaret A. Brimble, Kerry-Anne Rye, Rui Lu,