Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8632821 | Metabolism | 2018 | 49 Pages |
Abstract
Our data provide novel insights into the global molecular effects of HDL-apoA-I on endothelial cells and identify ANGPTL4 as a putative mediator of the atheroprotective functions of HDL-apoA-I on the artery wall, with notable therapeutic potential.
Keywords
MicroarraysJun N-terminal kinaseLPLANGPTL4EBMRCTCHXGCKIPAHAECseNOSApoA-IMCP-1qRT-PCRERKFOXO1PI3KCETPFPLCHDLICAM-1LPDsSmall interfering RNAsiRNAApolipoprotein A-Iendothelial NO synthasecardiovascular diseaseIngenuity Pathway AnalysisForkhead box O1CVDquantitative reverse transcription PCRfast protein liquid chromatographyEndothelial cellshuman aortic endothelial cellscycloheximidePhosphatidylinositol 3-kinaseLipoprotein lipasehigh density lipoproteinendothelial cell basal mediumIntercellular adhesion molecule 1Nitric oxidepolymerase chain reactionPCRmonocyte chemoattractant protein 1cholesterol ester transfer proteinreverse cholesterol transportlipoprotein deficient serumextracellular signal-regulated kinaseGlucokinase
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Authors
Dimitris Theofilatos, Panagiotis Fotakis, Efi Valanti, Despina Sanoudou, Vassilis Zannis, Dimitris Kardassis,