| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8632862 | Metabolism | 2018 | 31 Pages |
Abstract
These results indicate that canagliflozin may improve adipose tissue function and induce changes in serum leptin, adiponectin, and IL-6 that favorably impact insulin sensitivity and cardiovascular disease risk.
Keywords
GLIMTNFαLDL-CIL-6PPARγPAI-1SGLT2MCP-1HDL-CANCOVAVCAM-1CanagliflozinAdipokinesstandard deviationinterleukin-6Adipose tissueanalysis of covariancetumor necrosis factor αstandard errorType 2 diabetes mellitussodium glucose co-transporter 2confidence intervalCANVAShigh-density lipoprotein cholesterolPlasminogen activator inhibitor-1vascular cell adhesion molecule-1Biomarkersmonocyte chemoattractant protein-1C-reactive proteinCRPChemokinesLow-density lipoprotein cholesterolLeast squaresGlimepiridePeroxisome proliferator-activated receptor-γ
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Authors
W. Timothy Garvey, Luc Van Gaal, Lawrence A. Leiter, Ujjwala Vijapurkar, James List, Robert Cuddihy, Jimmy Ren, Michael J. Davies,