Article ID Journal Published Year Pages File Type
8632913 Metabolism 2018 39 Pages PDF
Abstract
ChREBP plays a key role in the dietary fructose transport as well as conversion into lactate and glucose through direct transcriptional control of genes involved in fructose transport, fructolysis, and gluconeogenesis. Moreover, ablation of Chrebp results in a severe diarrhea in mice fed a high-fructose diet, which is associated with the insufficient induction of GLUT5 in the intestine.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
Authors
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