Adiponectin receptor agonist AdipoRon decreased ceramide, and lipotoxicity, and ameliorated diabetic nephropathy

Article ID	Journal	Published Year	Pages	File Type
8632923	Metabolism	2018	35 Pages	PDF

Keywords

S1P 8-epi-prostaglandin F2α 8-epi-PGF2α GECs AMP-dependent kinase 8-OH-dG PGC-1 NEFA AMPK eNOS PPARα Col IV iNOS ACC TGF-β1 PP2A SREBP-1c 8-Hydroxy-2-deoxyguanosine F4/80 adiponectin acetyl-CoA carboxylase Sphingosine-1-phosphate nonesterified fatty acid endothelial NO synthase chronic kidney disease Transforming growth factor-β1 small interfering ceramide glomerular endothelial cell glomerular endothelial cells Lipotoxicity inducible nitric oxide synthase CKD Type IV collagen protein phosphatase 2A Peroxisome proliferator-activated receptor gamma coactivator-1α

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology

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Adiponectin receptor agonist AdipoRon decreased ceramide, and lipotoxicity, and ameliorated diabetic nephropathy

Authors

Sun Ryoung Choi, Ji Hee Lim, Min Young Kim, Eun Nim Kim, Yaeni Kim, Beom Soon Choi, Yong-Soo Kim, Hye Won Kim, Kyung-Min Lim, Min Jeong Kim, Cheol Whee Park,