Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8633000 | Metabolism | 2018 | 47 Pages |
Abstract
Because the liver is a central regulator of metabolic processes, it is important to understand how HBV replication and HBV protein expression affects the metabolic function of hepatocytes. Through analysis of a broad panel of metabolites we investigated this metabolic impact. The results of these studies have defined metabolic consequences of an HBV infection of hepatocytes and will help to lay the groundwork for novel research directions and, potentially, development of novel anti-HBV therapeutics.
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Authors
R. Jason Lamontagne, Jessica C. Casciano, Michael J. Bouchard,