Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8633009 | Metabolism | 2018 | 44 Pages |
Abstract
This study provided the first evidence that osmotin exerts preventive effects on vascular inflammation and atherosclerosis, which may facilitate the development of new therapeutic modalities for combating atherosclerosis and related diseases.
Keywords
phorbol 12-myristate 13-acetateECMAcyl-CoA:cholesterol acyltransferase 1PPARABCA1MCP-1HUVECICAM-1ANGIIVCAM-1AdipoRIL-6LPSMCMoxLDLMMPHASMCNF-κBPTX-3ATP-binding cassette transporter A1PMAAtherosclerosisAngiotensin IIOsmotininflammationinterleukin-6tumor necrosis factor-αHuman umbilical vein endothelial cellhuman aortic smooth muscle cellVascular smooth muscle cellEndothelial cellTNF-αnuclear factor-κBOxidized low-density lipoproteinlipopolysaccharideExtracellular matrixmatrix metalloproteinaseMacrophageintercellular adhesion molecule-1vascular cell adhesion molecule-1Monocyte chemotactic protein-1Pentraxin-3adiponectin receptorperoxisome proliferator-activated receptor
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Authors
Yui Takahashi, Rena Watanabe, Yuki Sato, Nana Ozawa, Miho Kojima, Kaho Watanabe-Kominato, Remina Shirai, Kengo Sato, Tsutomu Hirano, Takuya Watanabe,