Impact of systemic inflammation on the relationship between insulin resistance and all-cause and cancer-related mortality

Article ID	Journal	Published Year	Pages	File Type
8633049	Metabolism	2018	37 Pages	PDF

Abstract

Systemic inflammation can be used to stratify the subjects according to the all-cause and cancer-related mortality risks, irrespective of the insulin-resistance status. And this tendency is most pronounced in cancer-related mortality.

Keywords

CHD HDL-C GGT ICD-10 IGF-I NHANES ALT HOMA-IR SBP hs-CRP DBP LDL-C AST Aspartate aminotransferase Alanine aminotransferase inflammation insulin-like growth factor I interleukin coronary heart disease cardiovascular disease Triglycerides tumor necrosis factor-α CVD body mass index BMI confidence interval TNF-α diastolic blood pressure systolic blood pressure Blood pressure high-density lipoprotein cholesterol Mortality JUPITER Insulin resistance hazard ratio high-sensitivity C-reactive protein total cholesterol Low-density lipoprotein cholesterol Gamma-glutamyl transferase