| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8633146 | Metabolism | 2018 | 34 Pages |
Abstract
Whilst LOX may not be affected by obesity-associated complications such as diabetes, our results confirm that LOX is increased by hypoxia and inflammation as underlying mechanism for its upregulation in adipose tissue with obesity.
Keywords
LEPECMMCP-1LPSCOL6A1TGFbetaSVFTNFaHREHIF1aObstructive sleep apnoeascATinflammationLOXAdipose tissueSubcutaneous adipose tissueOsaDiabetesTransforming Growth Factor Betatumour necrosis factor alphaBariatric surgeryhypoxia-inducible transcription factorHypoxia-response elementFibrosisLeptinLysyl oxidaselipopolysaccharideExtracellular matrixObesityArbitrary Unitmonocyte chemoattractant protein-1Stromal vascular fraction
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Authors
Emilie Pastel, Emily Price, Kajsa Sjöholm, Laura J. McCulloch, Nikolaj Rittig, Neil Liversedge, Bridget Knight, Niels Møller, Per-Arne Svensson, Katarina Kos,