Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8633178 | Metabolism | 2017 | 27 Pages |
Abstract
In this study, we showed that NFIL3 functions as an important regulator of glucose homeostasis in the liver by limiting CREB-mediated hepatic gluconeogenesis. Thus, enhancement of hepatic NFIL3 activity in insulin resistant state could be potentially beneficial in relieving glycemic symptoms in the metabolic diseases.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Endocrinology
Authors
Geon Kang, Hye-Sook Han, Seung-Hoi Koo,