Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8633200 | Neuropeptides | 2018 | 11 Pages |
Abstract
In this review, we describe the various functions of apelin associated with AD and present an integrated overview of recent findings that, in general, recommend apelin as a promising therapeutic agent in the treatment of this ailment.
Keywords
AMPKPI3KJnkCATBACE1AβACEcGMPERKPTZMCP-1ABCA1RNSeNOSAPPeNOIP3ICVintracerebroventricularAVPGLP-1PKCNMDARinositol triphosphateAT1RNFTTGFQUINRAGEAAAGSKPLA2LRP-1MIP-1αAcetyl choline esteraseFDAOXSICAM-IAMP-activated protein kinaseATP-binding cassette transporter A1c-Jun N-terminal kinaseMPOGSH-PxI/RMAPKMitogen activated protein kinase kinasePKB/AKTROSHydrogen peroxideangiotensin converting enzymephospholipase A2Abdominal aortic aneurysmAChAChEApoeAcetylcholineQuinolinic acidendothelial nitric oxideischemia/reperfusioninterferonIFNinterleukinamyloid betaAlzheimer's diseaseAlzheimer diseasetransforming growth factorOxidative stresstumor necrosis factor alphaApelinCNSFood and Drug AdministrationSODBBBendothelial nitric oxide synthaseSuperoxide dismutasecentral nervous systemTNF-αphosphatidylinositide 3-kinasesBlood-brain barrierMEKSerum deprivationneurofibrillary tanglesmyeloperoxidaseNEPNeprilysinH2O2arginine vasopressinPresenilinMacrophage inflammatory protein-1αmonocyte chemoattractant protein-1amyloid precursor proteinprotein kinase BProtein kinase Cmitogen-activated protein kinasePentylenetetrazoleglucagon-like peptide-1Catalaseextracellular signal-regulated kinaseglutathione peroxidaseglycogen synthase kinaseGuanosine monophosphatereactive nitrogen speciesReactive oxygen speciesN-methyl d-aspartate receptorReceptor for advanced glycation end products
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Authors
Javad Masoumi, Morteza Abbasloui, Reza Parvan, Daryoush Mohammadnejad, Graciela Pavon-Djavid, Abolfazl Barzegari, Jalal Abdolalizadeh,